Systematic review: Efficacy and safety ofmedical marijuana in selected neurologic disorders
05 de Abril de 2017
Conclusions: The following were studied in patients with MS: (1) Spasticity: oral cannabis extract (OCE)
is effective, and nabiximols and tetrahydrocannabinol (THC) are probably effective, for reducing patientcentered
measures; it is possible both OCE and THC are effective for reducing both patient-centered
and objective measures at 1 year. (2) Central pain or painful spasms (including spasticity-related pain,
excluding neuropathic pain): OCE is effective; THC and nabiximols are probably effective. (3) Urinary
dysfunction: nabiximols is probably effective for reducing bladder voids/day; THC and OCE are probably
ineffective for reducing bladder complaints. (4) Tremor: THC and OCE are probably ineffective; nabiximols
is possibly ineffective.
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