Functional changes of the reward system underlie blunted response to social gaze in cocaine users
28 de Março de 2014
Social interaction deficits in drug users likely impede treatment, increase the burden of the affected families, and consequently contribute to the high costs for society associated with addiction. However, the neural origin contributing to altered social interaction in drug users is unknown thus far. The present study illuminates the nature of basic social interaction deficits as exemplified by social gaze behavior in cocaine users by applying behavioral, psychophysiological, and functional brain-imaging methods. The results suggest that basal social interaction impairments
probably arise from blunted social reward processing that was again related to impaired real-life social behavior in cocaine users. These results point to the importance of reinstatement of social reward in the treatment of stimulant addiction.
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