Sugar Industry and Coronary Heart Disease Research A Historical Analysis of Internal Industry Documents
11 de Outubro de 2016
Early warning signals of the coronary heart disease (CHD) risk of sugar (sucrose) emerged in
the 1950s.We examined Sugar Research Foundation (SRF) internal documents, historical
reports, and statements relevant to early debates about the dietary causes of CHD and
assembled findings chronologically into a narrative case study. The SRF sponsored its first
CHD research project in 1965, a literature review published in the New England Journal of
Medicine, which singled out fat and cholesterol as the dietary causes of CHD and downplayed
evidence that sucrose consumption was also a risk factor. The SRF set the review’s objective,
contributed articles for inclusion, and received drafts. The SRF’s funding and role was not
disclosed. Together with other recent analyses of sugar industry documents, our findings
suggest the industry sponsored a research program in the 1960s and 1970s that successfully
cast doubt about the hazards of sucrose while promoting fat as the dietary culprit in CHD.
Policymaking committees should consider giving less weight to food industry–funded studies
and include mechanistic and animal studies as well as studies appraising the effect of added
sugars on multiple CHD biomarkers and disease development.
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